We're in relentless pursuit of breakthroughs that change patients' lives. We innovate every day to make the world a healthier place.
To fully realize Pfizer's purpose – Breakthroughs that change patients' lives – we have established a clear set of expectations regarding "what" we need to achieve for patients and "how" we will go about achieving those goals.
Pfizer Research & Development serves as the beating heart of Pfizer's trailblazing product pipeline, the essence of our mission to bring life-changing medicines to the world.
Principal Analytical Scientist for Analytical Research & Development at the Ringaskiddy Clinical Manufacturing Facility, Cork Why Patients Need You Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. In Analytical Research & Development you will apply innovative measurement science, data analytics and process development capabilities to accelerate and bring the best-in-class medicines to patients around the world.
What You Will Achieve As a Principal Scientist in Analytical Research and Development, you will take an active role in supporting late-stage phases of pharmaceutical development by applying a variety of analytical methodologies to support physical and chemical characterization of drug substances. You will be significantly involved in supporting clinical manufacturing and process development through material testing, method development and transfer activities in and out of the RCMF analytical lab. You will perform qualitative and quantitative analyses of organic or inorganic compounds to determine chemical and physical properties during chemical syntheses. You will be using your scientific judgment to adapt standard methods and techniques by applying prior work experience.
Responsibilities Plan and perform laboratory work in support of analytical testing of pharmaceutical projects with experience in analytical methodologies: chromatography, KF, spectroscopy or mass spectrometry.Develop new analytical methods, method screening and troubleshoot analytical issues for methods in development and in use for clinical manufacturing.Lead methods transfers to and from the RCMF facility.Develop, verify and validate analytical methods across a range of techniques (HPLC, UPLC, GC, UV, KF, IR, SFC, MS, PSD).Review and verify scientific experiments and data documented in electronic laboratory notebooks.Mentor and coach junior team members to grow teams skill in analytical support.Collaborate with colleagues to identify appropriate analytical approaches, including use of computational predictive tools, modeling software and data visualization tools.Interact with project team members for various tasks including presentation of data and critical review of data and preparation of technical reports.Author relevant sections of global regulatory submissions in support of new drug approvals. Prepare technical reports, critically review data, and evaluate new instrumentation and analytical techniques/approaches.Demonstrate proficiency with a variety of software and information systems.Support day-to-day lab operations, ensuring that the performance metrics are in line with expectations for training, safety, quality/compliance.Education and Experience A PhD in analytical chemistry ideally combined with 7+ years' experience in the pharmaceutical industry, ideally within an analytical development role.A BSc/MSc in a degree with significant analytical focus plus 10 years' experience in the pharmaceutical industry, ideally within an analytical development role.Qualifications Must-Have
Experience in complex analytical investigation and method development and/or GMP experience.Experience in the use of general analytical techniques e.g HPLC, GC, KF, IR, LC-MS and UV.Experience in analytical method transfers.Ability to meet project milestones under minimal supervision, plan and manage priorities and expectations for specific projects.Experience in ensuring delivery of technology as well as submission-ready data and documents.Experience in problem-solving skills and instrument troubleshooting.Some experience in leading/managing small projects with demonstrated skills in planning, prioritization, and delivery of results.Demonstrated oral and written communication skills, including visualization of data and drafting reports.Experience with a variety of software and information systems (e.g. electronic lab notebooks, Empower and LIMS).Ability to work in a team environment in GMP laboratory environment performing experiments. Strong collaboration skills and experience working in a matrix environment.Demonstrated ability to learn new techniques and solve complex analytical problems.Ability to adhere to safe laboratory practices.Strong documentation skills with high attention to detail and strong organizational skills.Be team oriented, can multitask, and demonstrate effective interpersonal and communication skills.Nice-to-Have Experience in managing analytical development projects or sub-parts of projects.Experience in a GMP laboratory.Knowledgeable in vibrational spectroscopy (NIR, IR, Raman, UV-Vis).Process Analytics (PAT) experience potentially including modelling experience and/or PAT installation and set-up within a manufacturing facility.NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS Do not anticipate more than 10% travel.In order to be considered for this position in Ireland you need to be legally eligible to work in Ireland.
Closing Date: 3rd November 2024
How to apply Make a difference today, all suitable candidates should apply with CV below. We are looking forward to hearing from you!
#J-18808-Ljbffr