Job Title: Director, CPQP Data Programming Career Level - F Introduction to Role:
We are seeking a Director for PKPD Pharmacometric Data Programming to provide technical leadership and influence consistent approaches to data integration. This role is pivotal in preparing complex data to support translational modelling, population PK, PKPD, exposure-response, and disease modelling, and simulations in all clinical development phases. The CPQP Programming Director will be responsible for the design, implementation, maintenance and communication of technical solutions with pharmacometric programming. This role is an opportunity to apply state-of-the-art Pharmacometric Modeling and Simulation (M&S) data preparation approaches to influence designs and internal/external decision making at the project level.
Accountabilities:
As the Director, you will lead, develop and mentor a group of Programmers. You will use your project management skills to lead pharmacometric programming deliverables to support regulatory submissions. You will oversee the quality of all deliverables and hold partners accountable for their deliverable quality. You will also contribute to the development of best practices to improve quality, efficiency and effectiveness. You will be responsible for integrating internal (and external) data to support interpretation and decision making at the project level.
Essential Skills/Experience: 10+ years of industry experience with solid project management and delivery experienceDemonstrated leadership capabilitiesExtensive SAS programming expertise to an advanced levelExperience with pharmacometric or pharmacokinetic data and practicesComprehensive knowledge of technical and regulatory requirements related to the roleKnowledge of CDASH/SDTM/ADaM CDISC standardsExperience of regulatory submissionsDemonstrated managerial experienceDemonstrated ability to drive cross-functional infrastructure improvementsExcellent communication skillsExcellent collaboration required – needs the energy to work across global & functional boundariesAbility to apply programming expertise to problems, problem solving and quality focusExcellent knowledge in pharmacology, drug targets and core Therapy areas (e.g. Oncology, Respiratory, Renal Metabolism etc.)Varied programming languages (SAS, R, Python)Exposure to modelling tools– NONMEM, Stan, Monolix, etcBachelor's degreePreferred MS or PhD in Mathematical, Statistical, Computer Science or Life ScienceWhen we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.
At AstraZeneca's Biopharmaceuticals Business Unit, we are rethinking the way things can be done and acting on it. We go above and beyond to find solutions that impact patients - harnessing science with technology and connecting the entire healthcare ecosystem. It's our patients that come first, every decision we make and action we take is centred around how we can better serve them. We strive to create a place where everyone is empowered to speak up and share ideas, and we welcome alternative perspectives to push our thinking further, together.
Are you ready to fuel your ambition and break new ground? Join us in shaping patient care for the future! Apply now!
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